DMTCl44′Dimethoxytrityl CAS 40615-36-9
Kumenyekanisha DMTCl4 4 'Dimethoxytrityl - igisubizo cyanyuma cyo kurinda amatsinda neza, kurandura no kurinda hydroxyl kurinda nucleoside na nucleotide.Hamwe nubuziranenge budasanzwe ≥ 98%, iyi kristu yijimye yijimye itunganijwe neza kubushakashatsi bwawe bwose niterambere.
Ibikoresho bya Shimi
Kububiko, DMTCl4'Dimethoxytrityl isaba ubushyuhe bwa 2 kugeza 8 ° C kugirango bihamye neza.Nyamara, kubera ubuziranenge bwayo bwinshi, irashobora kubikwa igihe kirekire nta gutesha agaciro cyangwa gutakaza ubuziranenge.
Porogaramu
DMTCl44'Dimethoxytrityl nitsinda ririnda cyane itsinda rishinzwe kurinda amatsinda akora mungingo ngengabuzima nka amine, carboxyls na alcool.Ikoreshwa cyane muri synthesis organique na chimie peptide kugirango irinde amine yibanze nayisumbuye kuri reagent zitandukanye.
Usibye itsinda ryayo ririnda ubushobozi, DMTCl44'Dimethoxytrityl nayo ikuraho ishobora gukoreshwa mugukuraho hydroxyl mumatsinda ya nucleotide cyangwa nucleoside.Ibi ni ingirakamaro cyane muri synthesis ya nucleotide igereranya, aho kuba amatsinda ya hydroxyl ashobora kuganisha kumpande zidashaka.
Mubyongeyeho, DMTCl44'Dimethoxytrityl ikora nka hydroxyl nziza yo kurinda nucleoside na nucleotide.Irinda amatsinda ya hydroxyl kumwanya wa 3 'cyangwa 5' ya ribonucleoside cyangwa deoxyribonucleoside kugirango udashaka.
Muri make, niba ushaka uburyo bwiza bwo kurinda amatsinda, gukuraho no kurinda hydroxyl kurinda nucleoside na nucleotide, nta gisubizo cyiza kiruta DMTCl4 4 'Dimethoxytrityl.Hamwe nubuziranenge budasanzwe, koroshya ububiko hamwe nuburyo bwinshi bwo gukoresha, DMTCl4 4 'Dimethoxytrityl nibyiza kuri synthesis yawe yose hamwe na peptide ya chimie ikenera.