4,4'-Dimethoxytrityl chlorideni nucleoside ikomeye na nucleotide itsinda ririnda no gukuraho agent.
Synonym:DMT-Cl
Numero ya CAS:40615-36-9
Ibyiza
Imiti yimiti
Uburemere bwa molekile
Ubushyuhe Ububiko
Ingingo yo gushonga
Isuku
Inyuma
C21H19ClO2
338.82 g / mol
2 ~ 8 ℃
120-125 ℃
≥98%
Crystalline
Nkibice byingenzi bigize urunigi rwa acide nucleicide, nucleoside na nucleotide bigira uruhare runini mugukwirakwiza amakuru yimiterere.Nyamara, bitewe nubushakashatsi bwimiti no kwangirika byoroshye, nucleoside na nucleotide bisaba reagent kabuhariwe kugirango zibarinde mugihe cya synthesis.DMTCl4 'Dimethoxytrityl (DMTCl) nitsinda rikomeye cyane ririnda kandi rikuraho agent ryahinduye kurinda nucleoside na nucleotide mugihe cya synthesis.
DMTCl ni hydroxyl ikingira ibintu byihitiramo kwitabira hamwe nitsinda rya hydroxyl ya nucleoside na nucleotide mugihe cya synthesis kugirango bibe itsinda ririnda by'agateganyo ribuza nucleoside na nucleotide gukora hamwe nindi miti.Iri tsinda ririnda by'agateganyo rikurwaho byoroshye nyuma ya synthesis, hasigara nucleoside cyangwa nucleotide.
Bitewe nuburyo bwiza bwo gukora no guhitamo,DMTClikoreshwa cyane nkitsinda ririnda no gukuraho agent muri synthesis ya ADN, RNA nandi acide nucleic.Ni ingirakamaro cyane kuri synthesis ya oligonucleotide aho bisabwa kugenzura neza imyanya ya nucleotide hamwe nurutonde.
Usibye gukora nk'itsinda ririnda kandi rikuraho, DMTCl ni hydroxyl irinda nucleoside na nucleotide.Irinda hydroxyl matsinda ya nucleoside na nucleotide kwirinda okiside, kugabanuka, nibindi bitekerezo bishobora kubangiza mugihe cya synthesis.
Muri make,DMTCl4 4 'dimethoxytritylni igikoresho cyingenzi cyo guhuza nucleoside na nucleotide.Ubwiza buhebuje, guhitamo no guhinduka bituma itsinda ryiza ririnda kandi rikuraho agent na hydroxyl ikingira ADN, RNA hamwe na synthesis ya nucleic aside.Niba ukeneye uburinzi buhanitse kandi bwizewe bwa nucleoside na nucleotide mugihe cya synthesis, reba kure ya DMTCl.
Igihe cyo kohereza: Jun-08-2023